Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice

Richter, E; Schäfer, SG

HERO ID

4968657

Reference Type

Journal Article

Year

1982

Language

English

PMID

7096897

HERO ID 4968657
In Press No
Year 1982
Title Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice
Authors Richter, E; Schäfer, SG
Journal Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes
Volume 17
Issue 3 (1982)
Page Numbers 195-203
Abstract Female mice were given 100 mg HCB/kg body weight i.p. and fed diets containing 0, 2.5, 5.0, and 7.5% of squalane. After 3 weeks samples of liver, blood and abdominal fat were analysed for HCB as well as for squalane. HCB concentrations were significantly lowered as compared to controls in all tissues and at all dietary concentrations of squalane to a maximum of about 36% in fat, 44% in liver and 47% in blood. The effect of squalane upon HCB concentrations was strongly dose dependent in abdominal fat. In contrast, no significant differences were seen with liver and blood between animals fed 5.0 or 7.5% of squalane. Squalane was detected in considerable amounts in the livers (50-100 ppm) but not in abdominal fat (less than 1 ppm) of mice fed squalane.
Doi 10.1080/03601238209372313
Pmid 7096897
Wosid WOS:A1982NS81300001
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Index Medicus