Expedient synthesis and solvent dependent oxidation behaviour of a water-soluble IBX derivative
Kommeddy, A; Bowsher, MS; Gunna, MR; Botha, K; Vinod, TK
| HERO ID | 4854533 |
|---|---|
| In Press | No |
| Year | 2008 |
| Title | Expedient synthesis and solvent dependent oxidation behaviour of a water-soluble IBX derivative |
| Authors | Kommeddy, A; Bowsher, MS; Gunna, MR; Botha, K; Vinod, TK |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue | 28 |
| Page Numbers | 4378-4382 |
| Abstract | IBX derivative 6, synthesized in two steps from 2-aminoterephthalic acid, 8, is soluble in both DMF and water. A variety of alcohols are oxidized using 6 in DMF with ease and selectivity identical to that of parent IBX. However, oxidations carried out in water and other aqueous solvent mixtures using 6 exhibit unique selectivities toward different substrates and provide products different from reactions carried out in DMF. A mechanistic rationale is provided for this solvent dependent behavior of 6. Published by Elsevier Ltd. |
| Doi | 10.1016/j.tetlet.2008.05.017 |
| Wosid | WOS:000257194400016 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |