On the synthesis of beta-bromohydrine ethers via intermolecular alkoxyl radical addition to bicyclo[2.2.1]heptene

Hartung, J; Schneiders, N; Gottwald, T

HERO ID

4854510

Reference Type

Journal Article

Year

2007

HERO ID 4854510
In Press No
Year 2007
Title On the synthesis of beta-bromohydrine ethers via intermolecular alkoxyl radical addition to bicyclo[2.2.1]heptene
Authors Hartung, J; Schneiders, N; Gottwald, T
Journal Tetrahedron Letters
Volume 48
Issue 34
Page Numbers 6027-6030
Abstract Primary, secondary, and tertiary alkoxyl radicals add exo-selectively to the olefinic pi-bond in bicyclo[2.2.1]heptene to afford exo-2-alkoxybicyclo[2.2.1]kept-3-yl radicals, which are trapped with BrCCl3 preferentially from the endo face to furnish beta-bromohydrine ethers in 23-67% yield. (c) 2007 Elsevier Ltd. All rights reserved.
Doi 10.1016/j.tetlet.2007.06.103
Wosid WOS:000248985600024
Is Certified Translation No
Dupe Override No
Is Public Yes