[Rabbit eye irritation test]
Nakamura, K; Okamoto, K; Hamada, T; Mizutani, H; Ito, K; Ohata, S; Ogawa, T; Abe, T; Nakano, E; Et, AL
HERO ID
3041278
Reference Type
Technical Report
Year
1984
Language
Japanese
| HERO ID | 3041278 |
|---|---|
| Year | 1984 |
| Title | [Rabbit eye irritation test] |
| Authors | Nakamura, K; Okamoto, K; Hamada, T; Mizutani, H; Ito, K; Ohata, S; Ogawa, T; Abe, T; Nakano, E; Et, AL |
| Volume | 26 |
| Page Numbers | 1065-1074 |
| Abstract | We conducted the rabbit eye irritation test using the samples of three polyols (propylene glycol, 1, 3-butylene glycol and glycerin) as is and 10% in distilled water, and three hydrocarbons (liquid paraffin #72, squalane and pristane). Tests were performed in six labolatories, three with polyols and three with hydrocarbons. Comparing the reactions of three laboratories, propylene glycol and glycerin as is showed the same irritancy and 1, 3-butylene glycol showed a little lower irritancy than formers. 10% polyols and hydrocarbons showed low irritancy and no differences between the three chemicals were observed. By the way, no clear reduction effects of irritation by washing the eyes were seen. Though differences were shown in the grade of reactions between three laboratories, there was shown the same order as to the irritation grade of three chemicals. |
| Doi | 10.11340/skinresearch1959.26.1065 |
| Url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007966855&doi=10.11340%2fskinresearch1959.26.1065&partnerID=40&md5=70d15778d77e18200d18b14f27ef64dc |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | Japanese |