[Rabbit skin closed patch test]
Hamada, T; Mizutani, H; Ogawa, T; Abe, T; Nagura, T; Kuramoto, M
HERO ID
3041276
Reference Type
Journal Article
Year
1984
Language
Japanese
| HERO ID | 3041276 |
|---|---|
| In Press | No |
| Year | 1984 |
| Title | [Rabbit skin closed patch test] |
| Authors | Hamada, T; Mizutani, H; Ogawa, T; Abe, T; Nagura, T; Kuramoto, M |
| Journal | Skin Research |
| Volume | 26 |
| Issue | 5 |
| Page Numbers | 1084-1091 |
| Abstract | We performed the rabbit skin closed patch tests about the sefety evaluation method of cosmetic ingredients. Test materials include propylene glycol, 1, 3-butylene glycol, glycerin, liquid paraffin, squalane and pristane. This study was performed in three cosmetic companies. The results were as follows. (1) Clear positive reactions were seen only with propylene glycol and pristane. (2) Among the three polyols tested, the score of propylene glycol was the highest in primary irritant.There is no difference between 1, 3-butylene glycol and glycerin, and they showed only weak reactions. Pristane was a strong irritant as expected, but liquid paraffin and squalane showed only weak reactions. (3) As to propylene glycol, strong reactins were seen only with 100% but not with 30% and 10 concentrations. (4) Average score of each materials was different, but the order of irritant was the same in three lavoratories. |
| Doi | 10.11340/skinresearch1959.26.1084 |
| Url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007967178&doi=10.11340%2fskinresearch1959.26.1084&partnerID=40&md5=c9f84fa1b43bb169a3a03836295b1bc7 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | Japanese |