Reduction of dioxins and polychlorinated biphenyls (PCBs) in human body
Mochida, Y; Fukata, H; Matsuno, Y; Mori, C
HERO ID
2157468
Reference Type
Journal Article
Subtype
Review
Year
2007
Language
English
PMID
| HERO ID | 2157468 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2007 |
| Title | Reduction of dioxins and polychlorinated biphenyls (PCBs) in human body |
| Authors | Mochida, Y; Fukata, H; Matsuno, Y; Mori, C |
| Journal | Fukuoka Igaku Zasshi |
| Volume | 98 |
| Issue | 4 |
| Page Numbers | 106-113 |
| Abstract | The accumulation of persistent lipophilic organic pollutants like dioxins and PCBs in human body is of great concern since many of these compounds may elicit adverse health effects on humans. To reduce dioxins and PCBs with long half-lives that are absorbed into the human body, we need to work actively to minimize accumulation of dioxins and PCBs taken. Lot of manner has been tested such as foods containing dietary fibers and chlorophyll, lipids (squalane etc) and anion exchange resins. Cholestyramine, a cholesterol lowering agent, was no efficacy in humans. Authors have conducted a pilot study to demonstrate the effect lowering dioxin in human bodies using colestimide. Nine patients on cdestimide for 6 months, showed mean 20% decrease respectively in both dioxin and PCB levels, and the maximum percentage decrease was approximately 40%. From a standpoint to avoid the influence on high-risk group and high-risk life stage other than next generation, the world-wide cooperation for reducing environmental chemicals is greatly appealed. |
| Pmid | 17533984 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |