Safety evaluation of cosmetic raw materials
Guillot, JP; Martini, MC; Giauffret, JY
HERO ID
1619655
Reference Type
Journal Article
Year
1977
Language
English
| HERO ID | 1619655 |
|---|---|
| In Press | No |
| Year | 1977 |
| Title | Safety evaluation of cosmetic raw materials |
| Authors | Guillot, JP; Martini, MC; Giauffret, JY |
| Journal | Journal of the Society of Cosmetic Chemists |
| Volume | 28 |
| Page Numbers | 377-393 |
| Abstract | IPA COPYRIGHT: ASHP The toxicity of 26 cosmetics excipients was evaluated using a rabbit test. The ocular and cutaneous effects were evaluated using official French methods with some additions. The results show that 13 samples gave adverse reactions after repeated skin exposures; 8 of them appeared to be significantly more irritant--4 isopropyl myristates and 4 oleyl alcohols each from different sources. Eleven excipients were well tolerated when applied undiluted during 60 days and 2 gave uncertain results. Compounds tested included squalane, caprylic triglycerides, isopropyl myristate and palmitate, decyl oleate, octyl palmitate and stearate, oleyl alcohol and polyoxyethylene sorbitan stearate. |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>Excipients</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>cosmetics</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>toxicity</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Toxicity</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>excipients</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Squalane</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>cutaneous</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Caprylic triglycerides</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Isopropyl myristate</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Isopropyl palmitate</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Octyl palmitate</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Octyl stearate</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Alcohols</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Polyoxyethylene sorbitan stearate</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Methodology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>cosmetics</kw> |
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