Effects of perinatal polychlorinated biphenyls and dichlorodiphenyl dichloroethene on later development

Gladen, BC; Rogan, WJ

HERO ID

95109

Reference Type

Journal Article

Year

1991

Language

English

PMID

1906100

HERO ID 95109
In Press No
Year 1991
Title Effects of perinatal polychlorinated biphenyls and dichlorodiphenyl dichloroethene on later development
Authors Gladen, BC; Rogan, WJ
Journal Journal of Pediatrics
Volume 119
Issue 1 Pt 1
Page Numbers 58-63
Abstract Objective: Determining whether early developmental effects of perinatal exposure to polychlorinated biphenyls (PCBs) or dichlorodiphenyl dichloroethene (DDE) persist. Design: Cohort followed from birth; ages now 5 1/2 to 10 1/2 years. Setting: General community. Participants: Volunteer sample of 859 children, of whom 712 had been examinedwith the McCarthy Scales of Children's Abilities at 3, 4, or 5 years; 506 sent report cards. Interventions: None. Measurements and results: Neither transplacental nor breast-feeding exposure to PCBs or DDE affected McCarthy scores at 3, 4, or 5 years. There was no statistically significant relationship between poorer grades and PCB or DDE exposure by either route. Conclusions: The deficits seen in these children on the Bayley Scales of infantDevelopment through 2 years of age are no longer apparent.
Doi 10.1016/S0022-3476(05)81039-X
Pmid 1906100
Wosid WOS:A1991FV33000010
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
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