An evaluation of the associations of leukemia and rubber industry solvent exposures

Checkoway, H; Wilcosky, T; Wolf, P; Tyroler, H

HERO ID

94759

Reference Type

Journal Article

Year

1984

Language

English

PMID

6702828

HERO ID 94759
In Press No
Year 1984
Title An evaluation of the associations of leukemia and rubber industry solvent exposures
Authors Checkoway, H; Wilcosky, T; Wolf, P; Tyroler, H
Journal American Journal of Industrial Medicine
Volume 5
Issue 3
Page Numbers 239-249
Abstract HEEP COPYRIGHT: BIOL ABS. Excessive leukemia mortality has appeared consistently in epidemiological studies of British and USA rubber industry workers. Attempts to identify causative factors have focused on exposure to benzene and other solvents. Interpretations of findings from these studies have often been influenced by expectations of a benzene/nonlymphocytic leukemia association, seen from previous work in other settings. However, data from the rubber industry studies have not been consistent with this expectation, as lymphocytic and nonlymphocytic leukemia have shown similar mortality excesses. Data from a small case-control study of lymphocytic leukemia are presented to illustrate an approach that considers multiple solvent exposures. The associations with lymphocytic leukemia risk observed for a number of solvents, most notably carbon tetrachloride and carbon disulfide, were stronger than those detected for benzene.
Doi 10.1002/ajim.4700050307
Pmid 6702828
Wosid WOS:A1984SC25900006
Url https://www.proquest.com/scholarly-journals/evaluation-associations-leukemia-rubber-industry/docview/80995494/se-2?accountid=171501
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Solvents; 9006-04-6; Benzene; J64922108F; Index Medicus; Middle Aged; Solvents -- toxicity; Benzene -- toxicity; Leukemia -- chemically induced; Occupational Diseases -- chemically induced
Is Qa No