[Effects of personal exposure to nitrogen dioxide on peak expiratory flow in asthmatic patients]

Kwon, HJ; Lee, SG; Jee, YK; Lee, SR; Hwang, SS

HERO ID

90718

Reference Type

Journal Article

Year

2007

Language

Korean

PMID

17310600

HERO ID 90718
In Press No
Year 2007
Title [Effects of personal exposure to nitrogen dioxide on peak expiratory flow in asthmatic patients]
Authors Kwon, HJ; Lee, SG; Jee, YK; Lee, SR; Hwang, SS
Journal Journal of Preventive Medicine and Public Health
Volume 40
Issue 1
Page Numbers 59-63
Abstract OBJECTIVES: Nitrogen dioxide (NO2) has been inconsistently associated with gradual decreases in lung function. Here, we studied the effects of NO2 exposure in asthmatics by examining the association between changes in lung function and concentrations of NO2 which were personally measured. METHODS: Peak expiratory flow (PEF) and daily personal exposures to NO2 were recorded on 28 patients with asthma (confirmed by methacholine provocation test) over 4 weeks. We used generalized estimating equations to assess the relationship between personal NO2 exposure and PEF, adjusting for potential confounders such as age, gender, outdoor particulate matter, temperature, humidity, and exposure to environmental tobacco smoke. RESULTS: The personal NO2 exposures were higher than the corresponding ambient levels. The mean personal: ambient ratio for NO2 was 1.48. The personal NO2 exposures were not associated with the morning PEF, evening PEF, or the diurnal PEF variability. However, environmental tobacco smoke was negatively associated with both the morning and evening PEF. CONCLUSIONS: Among the asthmatic adults who participated in this study, we found no apparent impact of personal NO2 exposures on the peak expiratory flow.
Pmid 17310600
Is Certified Translation No
Dupe Override No
Comments ECRIB.J. Prev. Med. Public Health 40: 59-63.
Is Public Yes
Language Text Korean
Is Qa No