Simultaneous voltammetric determination for DA, AA and NO(2)(-) based on graphene/poly-cyclodextrin/MWCNTs nanocomposite platform

Zhang, Y; Yuan, R; Chai, Y; Li, W; Zhong, X; Zhong, H

HERO ID

901330

Reference Type

Journal Article

Year

2011

Language

English

PMID

21497078

HERO ID 901330
In Press No
Year 2011
Title Simultaneous voltammetric determination for DA, AA and NO(2)(-) based on graphene/poly-cyclodextrin/MWCNTs nanocomposite platform
Authors Zhang, Y; Yuan, R; Chai, Y; Li, W; Zhong, X; Zhong, H
Journal Biosensors and Bioelectronics
Volume 26
Issue 9
Page Numbers 3977-3980
Abstract In the present work, graphene sheets (GS) and multiwall carbon nanotubes (MWCNTs) were dispersed in the mixed solution of cyclodextrin (CD) and cyclodextrin prepolymer (pre-CD) and were used as modifier to fabricate chemical modified electrode to simultaneous detect dopamine (DA), ascorbic acid (AA) and nitrite (NO(2)(-)). CD cross-linked pre-CD (CDP) displays excellent film forming ability, which made the electrode stable. Comparing with CDP-GS, CDP-MWCNTs and CDP-GS-MWCNTs modified electrodes, the CDP-GS-MWCNTs displays higher catalytic activity and selectivity toward the oxidation of DA, AA and NO(2)(-), revealing that MWCNTs effectively inhibited the stacking of individual GS and enhanced the utilization of GS based composites. The host-guest chemical reaction ability of CD and π-π stacking interaction between detected molecules and GS-MWCNTs surface were considered as the main reasons of the successfully simultaneous detection of DA, AA and NO(2)(-). Cyclic voltammetry (CV), scanning electron microscopy (SEM) and different pulse voltammetry (DPV) were employed to characterize the biosensor. The linear response range for AA, DA and NO(2)(-) were 5μM-0.48mM, 0.15-21.65μM and 5μM-6.75mM, respectively and the detection limits were 1.65μM, 0.05μM and 1.65μM.
Doi 10.1016/j.bios.2011.03.017
Pmid 21497078
Wosid WOS:000291178200042
Is Certified Translation No
Dupe Override No
Comments Journal: Biosensors & bioelectronics ISSN: 1873-4235
Is Public Yes
Language Text English
Keyword Graphene sheets; Multiwall carbon nanotubes; Cyclodextrin; Dopamine; Ascorbic acid; Nitrite
Is Qa No