Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study
Colacino, JA; Soliman, AS; Calafat, AM; Nahar, MS; Van Zomeren-Dohm, A; Hablas, A; Seifeldin, IA; Rozek, LS; Dolinoy, DC
HERO ID
787925
Reference Type
Journal Article
Year
2011
Language
English
PMID
| HERO ID | 787925 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study |
| Authors | Colacino, JA; Soliman, AS; Calafat, AM; Nahar, MS; Van Zomeren-Dohm, A; Hablas, A; Seifeldin, IA; Rozek, LS; Dolinoy, DC |
| Journal | Environmental Health |
| Volume | 10 |
| Page Numbers | 40 |
| Abstract | Phthalates have been identified as endocrine active compounds associated with developmental and reproductive toxicity. The exposure to phthalates in premenstrual Egyptian females remains unknown. The objective of this study was to characterize phthalate exposure of a potentially vulnerable population of premenstrual girls from urban and rural Egypt.<br /><br /> We collected one spot urine sample from 60 10-13 year old females, 30 from rural Egypt, and 30 from urban Egypt from July to October 2009. Samples were analyzed for 11 phthalate metabolites. Additionally, we collected anthropometrics as well as questionnaire data concerning food storage behaviors, cooking practices, and cosmetic use. Phthalate metabolite concentrations were compared between urban and rural Egyptians as well as to age and gender matched Americans.<br /><br /> Monoethyl phthalate (MEP), was detected at the highest concentration in urine of Egyptian girls (median: 43.2 ng/mL in rural, 98.8 ng/mL in urban). Concentrations of urinary metabolites of di-(2-ethylhexyl) phthalate and dibutyl phthalate were comparable between Egyptians and age matched US girls. Storage of food in plastic containers was a statistically significant predictor of urinary mono-isobutyl phthalate (MiBP) concentrations when comparing covariate adjusted means.<br /><br /> Urinary concentrations of phthalate metabolites were similar in Egyptian and US populations, suggesting that phthalate exposure also occurs in developing nations. Dietary intake is likely an important route of exposure to phthalates in both urban and rural populations. |
| Doi | 10.1186/1476-069X-10-40 |
| Pmid | 21575223 |
| Wosid | WOS:000291559500001 |
| Url | https://search.proquest.com/docview/872127108?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science 000291559500001 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Adolescent; Child; Diet; Egypt; Environmental Exposure; Environmental Pollutants/classification/ toxicity/urine; Female; Food Packaging; Human Development/drug effects; Humans; Phthalic Acids/classification/ toxicity/urine; Pilot Projects; Rural Health; United States; Urban Health |
| Is Qa | No |