Perfluoroalkyl compounds
Garcia, JS; Harbison, RD
| HERO ID | 7486056 |
|---|---|
| Year | 2015 |
| Title | Perfluoroalkyl compounds |
| Book Title | Hamilton & Hardy's industrial toxicology (6th edition) |
| Authors | Garcia, JS; Harbison, RD |
| Editor | Harbison, RD; Bourgeois, MM; Johnson, GT |
| Publisher Text | John Wiley & Sons |
| City | Hoboken, New Jersey |
| Page Numbers | 689-718 |
| Abstract | This chapter discusses the physical and chemical properties of perfluoroalkyl compounds. Some of the perfluoroalkyl compounds includes: perfluoro butyl sulfonate (PFBS), perfluorobutyrate (PFBA), perfluorohexane sulfonate (PFHxS), perfluorohexanoic acid (PFHxA), perfluoroheptanoate (PFHpA), and perfluorooctane sulfonate (PFOS). It is believed that exposure to PFBS can result in acute effects, including changes in blood chemistry, hepatotoxicity, and nephrotoxicity. PFBA can result in acute effects, including changes in blood chemistry, hepatotoxicity, and thyroid dysfunction. Inhalation or dermal contact with PFBA can result in respiratory tract and skin irritation. Exposure to PFHxS was found to result in decreased body weight, decreased cholesterol levels, and increased prothrombin in rats. Some perfluoroalkyl chemicals, including PFHpA, have been linked to chronic effects associated with the liver, thyroid, and kidneys. Workers in direct or indirect contact may be at risk for PFUnA exposure. Inhalation and dermal contact are the most probable routes of exposure with ingestion not being likely. © 2015 by John Wiley & Sons, Inc. All rights reserved. |
| Doi | 10.1002/9781118834015.ch69 |
| Is Certified Translation | No |
| Dupe Override | No |
| Isbn | 9781118834015 |
| Edition | 6th |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018717680&doi=10.1002%2f9781118834015.ch69&partnerID=40&md5=32094bc1381a95c0513e937e23f2d436 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Hepatotoxicity; Nephrotoxicity; Perfluoro butyl sulfonate (PFBS); Perfluorobutyrate (PFBA); Perfluoroheptanoate (PFHpA); Perfluorohexane sulfonate (PFHxS); Perfluorohexanoic acid (PFHxA); Perfluorooctane sulfonate (PFOS) |