A cohort mortality study of cellulose triacetate-fiber workers exposed to methylene chloride

Gibbs, GW; Amsel, J; Soden, K

HERO ID

730533

Reference Type

Journal Article

Year

1996

Language

English

PMID

8823660

HERO ID 730533
In Press No
Year 1996
Title A cohort mortality study of cellulose triacetate-fiber workers exposed to methylene chloride
Authors Gibbs, GW; Amsel, J; Soden, K
Journal Journal of Occupational and Environmental Medicine
Volume 38
Issue 7
Page Numbers 693-697
Abstract The purpose of this study of 3211 cellulose-fiber production workers was to evaluate earlier findings of excess biliary tract and liver cancer in a similarly exposed cohort reported in 1990. Mortality from biliary tract and liver cancer was not increased in this study population, and there was no excess mortality from pancreatic cancer. Mortality was not elevated for cancers of the lung or liver, sites at which tumors were induced in experimental animals exposed to methylene chloride. Men with 20 or more years of employment exhibited increased mortality from prostate cancer, whereas women who also had 20 or more years of employment experienced higher-than-expected mortality from cervical cancer. Although these apparent increases in mortality are difficult to interpret biologically and are not consistent with previous studies, they require further investigation.
Doi 10.1097/00043764-199607000-00012
Pmid 8823660
Wosid WOS:A1996UX85200008
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English