Total deposition of aerosol particles in the human respiratory tract for nose and mouth breathing
Heyder, J; Armbruster, L; Gebhart, J; Grein, E; Stahlhofen, W
| HERO ID | 71322 |
|---|---|
| In Press | No |
| Year | 1975 |
| Title | Total deposition of aerosol particles in the human respiratory tract for nose and mouth breathing |
| Authors | Heyder, J; Armbruster, L; Gebhart, J; Grein, E; Stahlhofen, W |
| Journal | Journal of Aerosol Science |
| Volume | 6 |
| Issue | 5 |
| Page Numbers | 311-328 |
| Abstract | In five normal subjects the total deposition for nose- and mouth-breathing of monodisperse airborne di-2-ethylhexyl sebacate droplets in the diameter range from 0·1 to 3·2 μm was studied for a variety of breathing patterns without respiratory pauses. The calculation of deposition was based upon measurements of the particle number concentration and the respiratory flow rate at the mouth or the nose. For all subjects and all particle sizes deposition fell with increasing gas volume of the respiratory tract. However, when inhalations were initiated at the subjects' normal functional residual capacities no individual differences in deposition for mouth-breathing were found in contrast to nose-breathing deposition. For a constant flow rate the deposition rose with increasing tidal volume, whereas for a constant tidal volume the deposition fell with increasing breathing frequency indicating that time-dependent deposition mechanisms are more effective than velocity-dependent mechanisms. Whenever the mean residence time of the particles in the respiratory tract was short deposition for mouth-breathing was found to be almost independent of particle size in the diameter range below 1 μm revealing the significance of mixing. The deposition values obtained were lower than those usually accepted. The reasons for this are discussed. |
| Doi | 10.1016/0021-8502(75)90020-8 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |