Effect of the benzene fraction of petroleum on protein content in rat liver and kidney

Bong, M; Laskowska-Klita, T; Szymczyk, T

HERO ID

683921

Reference Type

Journal Article

Year

1985

Language

English

PMID

3971058

HERO ID 683921
In Press No
Year 1985
Title Effect of the benzene fraction of petroleum on protein content in rat liver and kidney
Authors Bong, M; Laskowska-Klita, T; Szymczyk, T
Journal Bulletin of Environmental Contamination and Toxicology
Volume 34
Issue 1
Page Numbers 45-54
Abstract Barr-Nea and Wolman in their studies on petroleum toxicity and carcinogenesis rubbed petroleum into the skin of mice and found that the animals developed malignant tumors of the lymphatic system and papilloma. The authors suggested that the effect observed was due to the presence in petroleum of aromatic hydrocarbons as well as hydrcarbons of different degree of oxidation. Although the benzene fraction of mineral oil contains only trace amounts of these types of hydrocarbons, it was found to cause hypertropy of hypophysis and adrenal cortex in animals subjected to chronic intoxication. In the present work the authors demonstrated that the R-33 benzene fraction of petroleum caused in the rat, hypertrophy of liver and kidney, changes in total protein content in these organs and changes in the protein synthetizing system, both when it was applied intraperitoneally and in the form of chronic inhalation of vapors.
Doi 10.1007/BF01609701
Pmid 3971058
Wosid WOS:A1985TZ54000007
Url https://www.proquest.com/scholarly-journals/effect-benzene-fraction-petroleum-on-protein/docview/14441070/se-2?accountid=171501
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Animals; Benzene/*toxicity; Kidney/*metabolism; Leucine/metabolism; Liver/*metabolism; Male; Microsomes/metabolism; Microsomes, Liver/metabolism; Organ Size/drug effects; Petroleum/*toxicity; Proteins/*metabolism; Rats; Rats, Inbred Strains
Is Qa No