Effects of three features of a job-exposure matrix on risk estimates

Dosemeci, M; Cocco, P; Gómez, M; Stewart, PA; Heineman, EF

HERO ID

632334

Reference Type

Journal Article

Year

1994

Language

English

PMID

8117771

HERO ID 632334
In Press No
Year 1994
Title Effects of three features of a job-exposure matrix on risk estimates
Authors Dosemeci, M; Cocco, P; Gómez, M; Stewart, PA; Heineman, EF
Journal Epidemiology
Volume 5
Issue 1
Page Numbers 124-127
Abstract We tested the impact of three features of a job-exposure matrix on risk estimates in a case-control study that evaluated the association of methylene chloride and astrocytic brain cancer. These features were probability of use of the agent; the consideration of decade of predominant use of methylene chloride within each occupation; and the use of a more specific industrial-occupational coding system. We compared the risk estimates obtained with and without these features. The introduction of each feature had a striking effect on the estimate of relative risk. The odds ratio ranged from 1.47 with none of these features, to 2.47 with high probability of exposure within industry and occupation, to 4.15 with high probability of exposure and specific industrial-occupational coding, to 6.08 with the three features together. These results indicate that the degree of exposure misclassification can be reduced by the introduction of these features into the job-exposure matrix.
Pmid 8117771
Wosid WOS:A1994MQ00800019
Url http://www.jstor.org/stable/3703013
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword MISCLASSIFICATION; EXPOSURE ASSESSMENT; EXPOSURE CATEGORIZATION; JOB-EXPOSURE MATRICES; OCCUPATIONAL EXPOSURES; EPIDEMIOLOGIC METHODS; DATA COLLECTION; BIAS
Is Qa No