Optic neuritis with residual tunnel vision in perchloroethylene toxicity
Onofrj, M; Thomas, A; Paci, C; Rotilio, D
HERO ID
630861
Reference Type
Journal Article
Year
1998
Language
English
PMID
| HERO ID | 630861 |
|---|---|
| In Press | No |
| Year | 1998 |
| Title | Optic neuritis with residual tunnel vision in perchloroethylene toxicity |
| Authors | Onofrj, M; Thomas, A; Paci, C; Rotilio, D |
| Journal | Journal of Toxicology: Clinical Toxicology |
| Volume | 36 |
| Issue | 6 |
| Page Numbers | 603-607 |
| Abstract | CASE REPORT: In a 57-year-old female owner of a dry-cleaning shop, we describe the association of severe bilateral optic neuritis with unexpectedly high concentrations of perchloroethylene/metabolites in the blood and of chloroform in urine. Visual disturbances consisted of complete blindness for 9 days in the left eye, for 11 days in the right eye, with bright phosphenes and pain on eye rotation. Only central (2-3 degrees radius) vision recovered in the following months. CONCLUSION: Although environmental concentrations of perchloroethylene were within normal limits, we measured five-fold increases in vapors emitted when ironing freshly dry-cleaned fabrics, and suggest that inhalation of perchloroethylene vapors was the cause of this case of ocular nerve toxicity, recapitulating a previous report of major perchloroethylene toxicity |
| Pmid | 9776966 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Blindness; blood; chemically induced; Chloroform; drug effects; Female; Humans; Italy; Magnetic Resonance Imaging; Middle Aged; Occupational Diseases; Optic Neuritis; Phosphenes; poisoning; Solvents; Tetrachloroethylene; toxicity; urine |
| Is Qa | No |
| Relationship(s) |
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