Exposure to solvents in female patients with scleroderma
Czirják, L; Kumánovics, G
HERO ID
630458
Reference Type
Journal Article
Year
2002
Language
English
PMID
| HERO ID | 630458 |
|---|---|
| In Press | No |
| Year | 2002 |
| Title | Exposure to solvents in female patients with scleroderma |
| Authors | Czirják, L; Kumánovics, G |
| Journal | Clinical Rheumatology |
| Volume | 21 |
| Issue | 2 |
| Page Numbers | 114-118 |
| Abstract | The role of exposure to solvents was investigated in female patients with connective tissue disease and Raynaud's phenomenon using a questionnaire. Sixteen out of the 63 patients with systemic sclerosis had been exposed to solvents. A borderline significance was demonstrated compared to matched female controls (P < 0.05). Fourteen out of the 66 patients with undifferentiated connective tissue disease, 18/86 of patients with Raynaud's phenomenon, 6/45 with systemic lupus erythematosus, 1/16 with dermatopolymyositis, 1/15 with rheumatoid arthritis and 0/13 with primary Sjogren's syndrome had been exposed to solvents. None of these groups of patients showed a statistical significance compared to matched controls. Our present findings indicate that, at least in certain areas of the world, exposure to solvents may be a provoking factor in female scleroderma, but it must be emphasised that only a borderline significance was found between the scleroderma patients and controls. A large multicenter study seems to be required to clarify the importance of solvents as provoking factors of scleroderma. Furthermore, exposure to solvents does not seem to be a provoking factor among females for the other connective tissue diseases |
| Doi | 10.1007/PL00011216 |
| Pmid | 12086160 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Adult; adverse effects; Age Distribution; Case-Control Studies; Cohort Studies; diagnosis; epidemiology; etiology; Female; Humans; Hungary; immunology; Incidence; Lupus Erythematosus,Systemic; Middle Aged; Occupational Exposure; Probability; Prognosis; Raynaud Disease; Reference Values; Risk Assessment; Scleroderma,Systemic; Solvents |
| Is Qa | No |