Delayed reproductive effects following exposure to toxic chemicals during critical developmental periods

Gray LE Jr

HERO ID

627423

Reference Type

Technical Report

Year

1989

Language

English

HERO ID 627423
Year 1989
Title Delayed reproductive effects following exposure to toxic chemicals during critical developmental periods
Authors Gray LE Jr
Publisher Text U.S. Environmental Protection Agency
City Research Triangle Park, NC
Volume NTIS
Page Numbers 54 pp
Abstract The studies presented in this review indicate that perinatal exposure of the fetal or neonatal rodent to a toxicant can adversely affect reproductive development, reduce fertility and accelerate reproductive senescence. In rodents and humans exposure to DES, estrogens, androgens and progestins during critical developmental periods produce morphological and pathological alterations of the reproductive tract of males and females. DES treatment causes cancer, infertility and serious morphological abnormalities of the reproductive tract in all species examined.
Report Number EPA/600/D-89/150
Is Certified Translation No
Dupe Override No
Comments Journal: NTIS Technical Report ISSN:
Is Public Yes
Language Text English
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