Estimating human exposure through multiple pathways from air, water, and soil
Mckone, TE; Daniels, JI
HERO ID
626198
Reference Type
Journal Article
Year
1991
Language
English
PMID
| HERO ID | 626198 |
|---|---|
| In Press | No |
| Year | 1991 |
| Title | Estimating human exposure through multiple pathways from air, water, and soil |
| Authors | Mckone, TE; Daniels, JI |
| Journal | Regulatory Toxicology and Pharmacology |
| Volume | 13 |
| Issue | 1 |
| Page Numbers | 36-61 |
| Abstract | This paper describes a set of multipathway, multimedia models for estimating potential human exposure to environmental contaminants. The models link concentrations of an environmental contaminant in air, water, and soil to human exposure through inhalation, ingestion, and dermalcontact routes. The relationship between concentration of a contaminant in an environmental medium and human exposure is determined with pathway exposure factors (PEFs). A PEF is an algebraic expression that incorporates information on human physiology and lifestyle together with models of environmental partitioning and translates a concentration (i.e., mg/m3 in air, mg/liter in water, or mg/kg in soil) into a lifetime-equivalent chronic daily intake (CDI) in mg/kg-day. Human, animal, and environmental data used in calculating PEFs are presented and discussed. Generalized PEFs are derived for air → inhalation, air → ingestion, water → inhalation, water → ingestion, water → dermal uptake, soil → inhalation, soil → ingestion, and soil → dermal uptake pathways. To illustrate the application of the PEF expressions, we apply them to soil-based contamination of multiple environmental media by arsenic, tetrachloroethylene (PCE), and trinitrotoluene (TNT). |
| Doi | 10.1016/0273-2300(91)90040-3 |
| Pmid | 2024045 |
| Wosid | WOS:A1991EX21200004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | |WOS:A1991EX21200004Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025977301&doi=10.1016%2f0273-2300%2891%2990040-3&partnerID=40&md5=09b386822e193de302a873cf7bbea1a7 |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>Mathematical Biology and Statistical Methods</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Biochemical Methods-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Biochemical Studies-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Digestive System-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Respiratory System-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Integumentary System-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Routes of Immunization</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Toxicology-Environmental and Industrial Toxicology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Public Health: Environmental Health-Air</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Hominidae</kw> |
| Is Qa | No |