The mutagenicity of nitro-aromatic compounds in the environment
Matsuda, A
| HERO ID | 625905 |
|---|---|
| In Press | No |
| Year | 1981 |
| Title | The mutagenicity of nitro-aromatic compounds in the environment |
| Authors | Matsuda, A |
| Journal | Gifu Daigaku Igakubu Kiyo |
| Volume | 29 |
| Issue | 2 |
| Page Numbers | 278-296 |
| Abstract | The mutagenicities of 26 nitro-aromatic compounds and their 10 related compounds for Salmonella typhimurium TA 100 and TA 98 were tested both with and without (mammalian) S-9 mix. The mutagenicities of the products formed by exposing pyrene to NO2 and and SO2 gases were tested for TA 98 without S-9 mix. Nine of 10 polynucleararomatic compounds without the nitro groups were nonmutagenic for both TA 100 and TA 98 with or without S-9 mix. Of 26 nitro-aromatic compounds, 24 were mutagenic for TA 100 and/or TA 98 with or without S-9 mix. All of 6 carcinogenic nitro compounds tested were mutagenic in this test. The specific mutagenic activities of nitroaromatic compounds became higher as the numbers of fused rings and nitro groups increased. The specific mutagenic activities of nitro-aromatic compounds with 3 or 4 fused rings were higher without S-9 mix than with S-9 mix for both TA 100 and TA 98. The reaction of pyrene with NO2 gas (nitration) was enhanced by SO2 gas. |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019452718&partnerID=40&md5=6373851a368786c0edc12233961f444c |
| Is Public | Yes |
| Language Text | Japanese |
| Is Qa | No |