Contact sensitivity to acrylate compounds in guinea pigs
Parker, D; Turk, JL
HERO ID
61412
Reference Type
Journal Article
Year
1983
Language
English
PMID
| HERO ID | 61412 |
|---|---|
| In Press | No |
| Year | 1983 |
| Title | Contact sensitivity to acrylate compounds in guinea pigs |
| Authors | Parker, D; Turk, JL |
| Journal | Contact Dermatitis |
| Volume | 9 |
| Issue | 1 |
| Page Numbers | 55-60 |
| Abstract | As reports of contact dermatitis in humans due to acrylate compounds have increased considerably in recent years, it was decided to investigate the ability of these chemicals to evoke contact sensitivity skin reactions in guinea pigs. 21 different acrylate and methacrylate compounds were scanned for their ability to induce contact sensitivity, using 5 different sensitization protocols. Contact reactions of varying intensities were produced to all the mono-, di- and triacrylates tested. However, it was not possible to sensitize guinea pigs to any methacrylates. It would appear that guinea pigs cannot be contact sensitized to acrylate chemicals that are substituted on carbon 2. |
| Doi | 10.1111/j.1600-0536.1983.tb04626.x |
| Pmid | 6839739 |
| Wosid | WOS:A1983PZ84500009 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |