IMPACT OF CHLOROPRENE AND ITS DERIVATIVES ON FERMENTAL SYSTEMS IN WORKERS ENGAGED IN THE PRODUCTION OF SYNTHETIC RUBBER

Khlgatyan, DS; Nersesova, LS; Gazaryants, MG; Mkrtchyan, ZS; Meliksetyan, GO; Pogosyan, LG; Kostandyan, SR; Akopyan, ZI

HERO ID

610310

Reference Type

Journal Article

Year

2009

HERO ID 610310
In Press No
Year 2009
Title IMPACT OF CHLOROPRENE AND ITS DERIVATIVES ON FERMENTAL SYSTEMS IN WORKERS ENGAGED IN THE PRODUCTION OF SYNTHETIC RUBBER
Authors Khlgatyan, DS; Nersesova, LS; Gazaryants, MG; Mkrtchyan, ZS; Meliksetyan, GO; Pogosyan, LG; Kostandyan, SR; Akopyan, ZI
Journal Toksikologicheskii Vestnik
Issue 2
Page Numbers 9-13
Abstract Labor conditions of workers engaged in chloroprene rubber production are characterized by exposure to a complex of chemical compounds among which the leading part is played by chloroprene and products Of its interaction with hydroxyl radicals and atmospheric ozone. It was shown with certainty that the activity of creatine kinase and purine nucleoside phosphorylase decreases 2-fold as compared to the control in blood serum Of workers engaged in chloroprene synthesis. Changes in enzymes activity are not related to gender, age or length of service. Activity of serumal alanine aminotransferase (ALT) and aspartate aminotransferase(AST) did not revealed any changes in those workers.
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