Air pollution and daily mortality in two US counties: season-specific analyses and exposure-response relationships

Moolgavkar, SH

HERO ID

51316

Reference Type

Journal Article

Year

2003

Language

English

PMID

12872178

HERO ID 51316
In Press No
Year 2003
Title Air pollution and daily mortality in two US counties: season-specific analyses and exposure-response relationships
Authors Moolgavkar, SH
Journal Inhalation Toxicology
Volume 15
Issue 9
Page Numbers 877-907
Abstract I used generalized additive models to analyze the time series of daily total nonaccidental deaths and deaths due to vascular disease over the period 1987-1995 in two major metropolitan areas, Cook County, Illinois, and Los Angeles County, California, in the United States. In both counties I had monitoring information on PM10, CO, SO2, NO2, and O3. In Los Angeles, monitoring information on PM2.5 was available as well. In addition to full-year analyses, I performed season-specific analyses. I present the results of both single- and multipollutant analyses. Although components of air pollution were associated with total nonaccidental and vascular disease mortality in both counties, the results indicate considerable heterogeneity of these associations in the two locations and also from season to season. In Los Angeles County, the gases, particularly CO and SO2 but not ozone, were more strongly associated with mortality than was particulate matter, which exhibited only weak and inconsistent associations with both mortality endpoints. Both PM10 and the gases were associated with total and vascular disease mortality in Cook County. The association of the gases with both mortality endpoints appeared to be stronger and more robust than that of PM10. Exposure-response analyses using flexible smoothers showed significant departures from linearity, particularly for PM effects.
Doi 10.1080/08958370390215767
Pmid 12872178
Wosid WOS:000184470900002
Url http://search.proquest.com/docview/17899561?accountid=102841
Is Certified Translation No
Dupe Override No
Comments ECRIB. 2003b in 1640,AX5.Inhalation Toxicol. 15: 877-907.
Is Public Yes
Language Text English
Keyword Toxicology Abstracts; man; Inhalation; Air pollution; Mortality; USA, Illinois; USA, California; Seasonal variations; X 24240:Miscellaneous
Is Peer Review Yes