Malignant pleural mesothelioma: a comprehensive review
Ismail-Khan, R; Robinson, LA; Williams, CC, Jr; Garrett, CR; Bepler, G; Simon, GR
HERO ID
5085738
Reference Type
Journal Article
Year
2006
Language
English
| HERO ID | 5085738 |
|---|---|
| In Press | No |
| Year | 2006 |
| Title | Malignant pleural mesothelioma: a comprehensive review |
| Authors | Ismail-Khan, R; Robinson, LA; Williams, CC, Jr; Garrett, CR; Bepler, G; Simon, GR |
| Volume | 13 |
| Issue | 4 |
| Page Numbers | 255-263 |
| Abstract | BACKGROUND: The incidence of malignant mesothelioma continues to increase, but the disease remains difficult to detect early and treat effectively. METHODS: The authors review the pathogenesis, incidence, clinical presentation, diagnosis, pathology, and both standard and experimental treatments for mesothelioma. RESULTS: When possible, surgery (video-assisted thoracoscopy, pleurectomy/decortication, or extrapleural pneumonectomy) is utilized. Effects on underlying structures limit application of radiation therapy, but some systemic agents are beginning to enhance survival. CONCLUSIONS: The disease is expected to increase in incidence till 2020, so awareness of this entity as a possible diagnosis should be heightened. In patients with advanced disease, several newer antitumor agents are already showing a capability of extending survival so it is not unreasonable to expect further progress in this area. |
| Doi | 10.1177/107327480601300402 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: Cancer control : journal of the Moffitt Cancer Center ISSN: 748 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Humans; Incidence; Magnetic Resonance Imaging; Mesothelioma/diagnosis/epidemiology/therapy; Neoplasm Staging; Pleural Effusion, Malignant/diagnosis/etiology/therapy; Pleural Neoplasms/complications/diagnosis/epidemiology/therapy; Tomography, X-Ray Computed; United States/epidemiology |