Short-term effects of calcium carbonate, lactate, and gluconate on the calcium-parathyroid axis in normal elderly men and women
Goddard, M; Young, G; Marcus, R
HERO ID
4946441
Reference Type
Journal Article
Year
1986
Language
English
PMID
| HERO ID | 4946441 |
|---|---|
| In Press | No |
| Year | 1986 |
| Title | Short-term effects of calcium carbonate, lactate, and gluconate on the calcium-parathyroid axis in normal elderly men and women |
| Authors | Goddard, M; Young, G; Marcus, R |
| Journal | American Journal of Clinical Nutrition |
| Volume | 44 |
| Issue | 5 |
| Page Numbers | 653-658 |
| Abstract | We evaluated the impact of three calcium salts on the calcium-parathyroid axis in healthy elderly volunteers. Fasting subjects were administered a standardized 1-g calcium load on three occasions, using calcium carbonate, lactate, and gluconate in random sequence with 8 oz milk or orange juice as carrier. Blood and urine were collected at baseline and for 6 h following the calcium load. Each salt rapidly increased the serum-calcium concentration and urinary-calcium excretion. Response duration was shorter with gluconate than with the other salts, but peak responses were similar for all preparations. Urinary-calcium excretion was slightly lower when orange juice replaced milk, but calcemic responses were not different. Changes in immunoreactive-parathyroid hormone and renal-phosphorus handling did not differ among calcium salts. Except for a shorter duration of effect with gluconate, all three calcium salts provided similar short-term suppression of the parathyroid axis. |
| Doi | 10.1093/ajcn/44.5.653 |
| Pmid | 3020960 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |