Toxicity of mono methyl ether of dipropylene glycol (Dowanol 50B) in studies on auricular fibrillation
Rucknagel, DL; Surtshin, A
HERO ID
4946053
Reference Type
Journal Article
Year
1952
Language
English
PMID
| HERO ID | 4946053 |
|---|---|
| In Press | No |
| Year | 1952 |
| Title | Toxicity of mono methyl ether of dipropylene glycol (Dowanol 50B) in studies on auricular fibrillation |
| Authors | Rucknagel, DL; Surtshin, A |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 80 |
| Issue | 4 |
| Page Numbers | 584-585 |
| Abstract | When administered intravenously to dogs anesthetized with pentobarbital, Dowanol 5OB in adequate dosage produces auricular fibrillation, but in 4 dogs was found unsuitable for use in repeated experiments on different days, since it caused respiratory depression, prolonged anesthesia, disturbances of gait, intestinal hemorrhages and death. One animal surviving a first experiment required a significantly higher single dose and higher cumulative dose for production of fibrillation during a second experiment and succumbed following the latter. |
| Doi | 10.3181/00379727-80-19699 |
| Pmid | 12983350 |
| Wosid | BCI:BCI19532700006639 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |