Gluconic Acid

Ramachandran, S; Nair, S; Larroche, C; Pandey, A

HERO ID

4944478

Reference Type

Book/Book Chapter

Year

2017

Language

English

HERO ID 4944478
Year 2017
Title Gluconic Acid
Book Title Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products
Authors Ramachandran, S; Nair, S; Larroche, C; Pandey, A
Publisher Text Elsevier
City Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands; The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, United Kingdom; 50 Hampshire Street, 5th Floor, Cambridge, MA 02139, United States
Volume Elsevier
Page Numbers 577-599
Abstract Gluconic acid is a multifunctional organic acid used as a bulk chemical in the food, feed, pharmaceutical, textile, metallurgy, detergent, paper, and construction industries. It is derived from glucose through a simple oxidation reaction catalyzed by glucose oxidase (EC 1.1.3.4.). Oxidation of the aldehyde group on C-1 of β-d-glucose to a carboxyl group results in the production of glucono-δ-lactone (C6H10O6) and hydrogen peroxide using molecular oxygen as the electron acceptor. Glucono-δ-lactone is further hydrolyzed to gluconic acid either spontaneously or by lactone-hydrolyzing enzyme. There are various approaches such as chemical, biochemical, and electrochemical available for its production, but microbial fermentation by Aspergillus niger using glucose oxidase is the most widely studied method. Microbial production of gluconic acid by bacteria, Gluconobacter, has also been demonstrated well. The enzyme involved in this process is glucose dehydrogenase. This chapter gives a review of microbial gluconic acid production; its recovery, properties, and applications; and the enzyme glucose oxidase.
Doi 10.1016/B978-0-444-63662-1.00026-9
Wosid WOS:000424738200027
Is Certified Translation No
Dupe Override No
Isbn 978-0-444-63662-1
Is Public Yes
Language Text English