Study of detrusor dysfunction due to outlet obstruction: link between analysis of uroflows of men with benign prostatic hyperplasia and animal studies
Valentini, FA; Levin, RM; Besson, GR; Nelson, PP
HERO ID
4936310
Reference Type
Book/Book Chapter
Year
2003
Language
English
PMID
| HERO ID | 4936310 |
|---|---|
| Year | 2003 |
| Title | Study of detrusor dysfunction due to outlet obstruction: link between analysis of uroflows of men with benign prostatic hyperplasia and animal studies |
| Book Title | Bladder disease: Research concepts and clinical applications, pts A and B |
| Authors | Valentini, FA; Levin, RM; Besson, GR; Nelson, PP |
| Editor | Atala, A; Slade, D |
| Publisher Text | Springer |
| City | Boston, MA |
| Volume | 539 |
| Page Numbers | 297-309 |
| Abstract | Bladder dysfunction secondary to benign prostatic hyperplasia (BPH) is a major affliction of aging men. BPH can initiate both irritative lower urinary tract symptoms (urgency, frequency, and nocturia), and obstructive symptoms (reduced flow rate, increased micturition pressure, increased duration of micturition, and incomplete emptying). Although these symptoms are related to the effect of the enlarging prostate and subsequent urethral obstruction, there appears to be no direct relationship between prostate size or composition and severity of symptoms.3,13,17,19,23 In addition, the results of standard urodynamic evaluations do not correlate well with the severity of patient symptoms; standard urodynamics cannot accurately predict either level of bladder pathology or potential for recovery following surgery.3,13,17,19,23 One major problem is that current methods of urodynamic analysis, including pressure measurements, are indirect assessments of detrusor power or contractile function. |
| Pmid | 15088913 |
| Wosid | WOS:000189426200022 |
| Is Certified Translation | No |
| Dupe Override | No |
| Conference Location | Washington, DC |
| Series | Advances in Experimental Medicine and Biology |
| Isbn | 9781461347071 |
| Conference Name | International Bladder Symposium |
| Conference Date | March 08-11, 2001 |
| Is Public | Yes |
| Language Text | English |