Synthesis of various substituted thieno[2',3'(or 3',2'):5,6]azepino[2,1-a]isoindol-6-ones
Pigeon, P; Decroix, B
| HERO ID | 4935919 |
|---|---|
| In Press | No |
| Year | 1997 |
| Title | Synthesis of various substituted thieno[2',3'(or 3',2'):5,6]azepino[2,1-a]isoindol-6-ones |
| Authors | Pigeon, P; Decroix, B |
| Journal | Bulletin de la Société Chimique de Paris |
| Volume | 134 |
| Issue | 2 |
| Page Numbers | 153-157 |
| Abstract | Study of the regioselectivity of addition of Grignard reagents onto imide ester 7 led to the expected phenyl derivative 12. By contrast, the methyl derivative 15 necessitated the use of a Mannich reaction onto the ketone 4. Finally, reaction of diethyl malonate with ketone 4 exhibited a dehydrogenation leading to a conjugate diester 19 and the expected diester 18. |
| Wosid | WOS:A1997WY71800004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | thienoazepine; isoindol-1-one; Mannich reaction; Knoevenagel condensation |