Theoretical development and performance evaluation for extractive fermentation using multiple extractants

Shi, Z; Shimizu, K; Iijima, S; Morisue, T; Kobayashi, T

HERO ID

4929616

Reference Type

Journal Article

Year

1990

Language

English

PMID

18595108

HERO ID 4929616
In Press No
Year 1990
Title Theoretical development and performance evaluation for extractive fermentation using multiple extractants
Authors Shi, Z; Shimizu, K; Iijima, S; Morisue, T; Kobayashi, T
Journal Biotechnology and Bioengineering
Volume 36
Issue 5
Page Numbers 520-529
Abstract Mathematical formulation was made for the performance evaluation of extractive fermentation using multiple solvents. Two types of solvent-supplying strategies were considered. One is to add multiple solvents simultaneously and the product is removed at one time. Another is to add them one by one consecutively. Computer simulation was made for batch, fed-batch, and repeated fed-batch operation of acetone-butanol fermentation to show the power of the approach. The result shows that the significant performance improvement in terms of the productivity and the product concentration is expected when two extractants such as oleyl alcohol and benzyl benzoate are used as compared with the case of using only one solvent.
Doi 10.1002/bit.260360511
Pmid 18595108
Is Certified Translation No
Dupe Override 4929616
Is Public Yes
Language Text English