CuI/L-proline-catalyzed coupling reactions of aryl halides with activated methylene compounds
Xie, X; Cai, G; Ma, D
| HERO ID | 4923608 |
|---|---|
| In Press | No |
| Year | 2005 |
| Title | CuI/L-proline-catalyzed coupling reactions of aryl halides with activated methylene compounds |
| Authors | Xie, X; Cai, G; Ma, D |
| Journal | Organic Letters |
| Volume | 7 |
| Issue | 21 |
| Page Numbers | 4693-4695 |
| Abstract | [reaction: see text] The arylation of ethyl acetoacetate, ethyl benzoyl acetate, and diethyl malonate under the catalysis of CuI/L-proline in DMSO proceeds smoothly at 40-50 degrees C in the presence of Cs2CO3 to provide the 2-aryl-1,3-dicarbonyl compounds in good yields. Both aryl iodides and aryl bromides are compatible with these reaction conditions. |
| Doi | 10.1021/ol0518838 |
| Pmid | 16209512 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |