L-Proline catalyzed reaction of N-confused porphyrin and active methylene compounds
Liu, B; Li, X; Zhang, J; Chmielewski, PJ
| HERO ID | 4923533 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | L-Proline catalyzed reaction of N-confused porphyrin and active methylene compounds |
| Authors | Liu, B; Li, X; Zhang, J; Chmielewski, PJ |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 11 |
| Issue | 29 |
| Page Numbers | 4831-4839 |
| Abstract | Active methylene compounds such as acetone, butanone, cyclopentanone, nitromethane, malononitrile, ethyl 2-cyanoacetate, diethyl malonate, and ethyl acetylacetate react with the C3 position of N-confused porphyrin in the presence of L-proline in refluxing THF-EtOH affording a variety of N-confused porphyrin derivatives in moderate yield. L-Proline catalyzes the reaction facilitating the formation of the carbanion derived from an active methylene compound simultaneously delivering protons to the N-confused porphyrin. Both processes are key factors of this reaction. |
| Doi | 10.1039/c3ob40754c |
| Pmid | 23797270 |
| Wosid | WOS:000322299100012 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |