Dust overloading of lungs after exposure of rats to particles of low solubility: Comparative studies
Muhle, H; Bellman, B; Creutzenberg, O; Heinrich, U; Ketkar, M; Mermelstein, R
| HERO ID | 4741 |
|---|---|
| In Press | No |
| Year | 1990 |
| Title | Dust overloading of lungs after exposure of rats to particles of low solubility: Comparative studies |
| Authors | Muhle, H; Bellman, B; Creutzenberg, O; Heinrich, U; Ketkar, M; Mermelstein, R |
| Journal | Journal of Aerosol Science |
| Volume | 21 |
| Issue | 3 |
| Page Numbers | 374-377 |
| Abstract | Dust overloading of lungs was reported in various studies (Ferin and Feldstein, 1978; Vostal et al., 1982; Vincent et al., 1985). We investigated this effect in a variety of subchronic and chronic inhalation studies after exposure to benign or slightly toxic insoluble materials. The characteristic findings were accumulation of large quantities of insoluble material in the lung, impairment of the alveolar clearance and an inflammatory response. |
| Doi | 10.1016/0021-8502(90)90062-3 |
| Wosid | WOS:A1990DE72300012 |
| Is Certified Translation | No |
| Dupe Override | No |
| Conference Location | Vienna, Austria |
| Conference Name | European Aerosol Conference |
| Conference Date | September, 1989 |
| Is Public | Yes |
| Language Text | English |