Combined effect of blood cadmium and lead levels on coronary heart disease prediction risk in Korean men
Cho, HM; Cho, DY; Kim, MY; Yang, SW; Seo, YS; Kim, KN
HERO ID
4651295
Reference Type
Journal Article
Year
2016
Language
English
PMID
| HERO ID | 4651295 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | Combined effect of blood cadmium and lead levels on coronary heart disease prediction risk in Korean men |
| Authors | Cho, HM; Cho, DY; Kim, MY; Yang, SW; Seo, YS; Kim, KN |
| Journal | Angiology |
| Volume | 67 |
| Issue | 6 |
| Page Numbers | 582-586 |
| Abstract | This study was designed to investigate the combined effects of cadmium (Cd) and lead (Pb) on 10-year coronary heart disease (CHD) risk calculated using the Framingham risk score. The heavy metal data set of the Korean National Health and Nutrition Examination Survey IV and V (2008-2010) was analyzed. The 10-year CHD risk was significantly associated with the log-transformed blood Cd and Pb levels in Korean men. For the highest quartile of Cd and Pb, the odds ratio (OR) of the intermediate risk and beyond for CHD (10-year risk ≥10%) compared to the lowest quartile was 6.870 (Cd, 95% confidence interval [CI]: 4.58-10.30) and 3.127 (Pb, 95% CI: 2.09-4.69) after adjusting for confounders, respectively. The adjusted OR of the intermediate risk and beyond for CHD (10-year risk ≥10%) in the fourth quartile of both Cd and Pb was 12.2 (95% CI: 8.0-18.5) compared to the reference group (first and second quartiles of Cd and Pb). However, the association between log-transformed blood Cd and Pb and the 10-year CHD risk was not significant in Korean women. |
| Doi | 10.1177/0003319715605954 |
| Pmid | 26586853 |
| Wosid | WOS:000377215900012 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | cadmium; lead; coronary heart disease; Framingham risk score |
| Is Peer Review | Yes |