Alcohol exposure during pregnancy altered childhood developmental trajectories in a rural South African community
Davies, LA; Cockcroft, K; Olinger, L; Chersich, M; Urban, M; Chetty Makkan, CM; Turnbull, OH; Olivier, L; Viljoen, D
| HERO ID | 4239598 |
|---|---|
| In Press | No |
| Year | 2017 |
| Title | Alcohol exposure during pregnancy altered childhood developmental trajectories in a rural South African community |
| Authors | Davies, LA; Cockcroft, K; Olinger, L; Chersich, M; Urban, M; Chetty Makkan, CM; Turnbull, OH; Olivier, L; Viljoen, D |
| Journal | Acta Paediatrica |
| Volume | 106 |
| Issue | 11 |
| Page Numbers | 1802-1810 |
| Abstract | <strong>AIM: </strong>This study examined the effects of prenatal alcohol exposure on childhood development trajectories in a rural South African community between 2003 and 2008.<br /><br /><strong>METHODS: </strong>We assessed 121 children at 7-12 months (year one) and 5-6 years (year five) using the Griffiths Mental Developmental Scales - Extended Revised, which measures sensorimotor, cognitive and social development, with lower scores indicating developmental delay. We also interviewed their mothers or caregivers. Three groups were identified: 29 with foetal alcohol syndrome (FAS) or partial FAS (pFAS), 57 more who had been exposed to alcohol and 35 controls who had not.<br /><br /><strong>RESULTS: </strong>The scale's total score was higher in the controls than in the FAS/pFAS group at year one and year five and in the alcohol-exposed group at year five. Many groups' trajectories declined when compared with global norms, but the trajectories in the FAS/pFAS and the alcohol-exposed groups declined more than the controls for eye-hand and performance and total score. Earlier pregnancy recognition in the FAS/pFAS group correlated strongly (r = -0.77) with higher GQ in year five.<br /><br /><strong>CONCLUSION: </strong>FAS/pFAS and prenatal alcohol exposure affected the Griffiths scores more than the control group. Efforts are needed to detect pregnancy early and reduce alcohol exposure. |
| Doi | 10.1111/apa.13978 |
| Pmid | 28685855 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |