[Carcinogenic hazard of small doses of nitrite in connection with the endogenous synthesis of nitroso compounds]

Iurchenko, VA; Linnik, AB; Il'nitskiĭ, AP

HERO ID

4072560

Reference Type

Journal Article

Year

1986

Language

Russian

PMID

3948757

HERO ID 4072560
In Press No
Year 1986
Title [Carcinogenic hazard of small doses of nitrite in connection with the endogenous synthesis of nitroso compounds]
Authors Iurchenko, VA; Linnik, AB; Il'nitskiĭ, AP
Journal Eksperimental'naya Onkologiya
Volume 8
Issue 1
Page Numbers 41-44
Abstract Carcinogenic risk of small doses of precursors of nitroso compounds, i.e. sodium nitrite (total dose in 0.2-2.0 g/mouse in drinking water) and morpholine (total dose is 0.23 g/mouse in bread) was studied in 520 CBA and 290 C57Bl mice during 96 weeks. It is shown that under these conditions the carcinogenic effect was more pronounced in CBA mice: there was a significant increase in general incidence of tumours, particularly liver tumours and hemoblastoses in CBA females and malignant liver tumours in CBA males.
Pmid 3948757
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text Russian