Calcium and phosphorus retention in the preterm infant during total parenteral nutrition. A comparative randomised study between organic and inorganic phosphate as a source of phosphorus
Devlieger, H; Meyers, Y; Willems, L; de Zegher, F; Van Lierde, S; Proesmans, W; Eggermont, E
| HERO ID | 4002590 |
|---|---|
| In Press | No |
| Year | 1993 |
| Title | Calcium and phosphorus retention in the preterm infant during total parenteral nutrition. A comparative randomised study between organic and inorganic phosphate as a source of phosphorus |
| Authors | Devlieger, H; Meyers, Y; Willems, L; de Zegher, F; Van Lierde, S; Proesmans, W; Eggermont, E |
| Journal | Clinical Nutrition |
| Volume | 12 |
| Issue | 5 |
| Page Numbers | 277-281 |
| Abstract | The preterm infant fed parenterally is prone to some demineralisation due in part to insufficient Calcium (Ca) and Phosphorus (P) retention. In an attempt to augment Ca and P retention, we prepared a standardised parenteral solution containing calcium gluconate and glucose-1-phosphate (Phocytan) as source of phosphorus, yielding a daily supply of 75 mg/kg Ca and 45 mg/kg P. 28 very low birthweight infants were randomly assigned to receive either this solution (high Ca P ; n = 15) or a conventional formulation containing calcium gluconate and potassium mono- and dibasic phosphate delivering 42 mg/kg Ca and 36 mg/kg P daily (low Ca P ; n = 13). In the high Ca P daily retention was respectively 80% and 99% for Ca and P whereas in the low Ca P group, retention was 70% and 82%. Serum parathormone levels were significantly lower in the high Ca P group. We conclude that parenteral nutrition with a new high Ca P supplement results in an augmented Ca and P retention in very low birthweight infants. This may help to prevent neonatal bone demineralization. |
| Doi | 10.1016/0261-5614(93)90046-7 |
| Pmid | 16843326 |
| Wosid | WOS:A1993MF39900005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |