Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate
Hoke, RA; Ferrell, BD; Sloman, TL; Buck, RC; Buxton, LW
HERO ID
3980863
Reference Type
Journal Article
Year
2016
Language
English
PMID
| HERO ID | 3980863 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate |
| Authors | Hoke, RA; Ferrell, BD; Sloman, TL; Buck, RC; Buxton, LW |
| Journal | Chemosphere |
| Volume | 149 |
| Page Numbers | 336-342 |
| Abstract | The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the available data suggest low risk to aquatic organisms. |
| Doi | 10.1016/j.chemosphere.2016.01.009 |
| Pmid | 26874062 |
| Wosid | WOS:000372760100041 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Aquatic toxicity; Bioconcentration; Hazard assessment; Risk assessment; Perfluoroalkyl substances |