Perfluoroalkyl substances in the blood samples from a male population of Sweden

Bao, Jia; Karrman, A; van Bavel, B; Jin, Y

HERO ID

3860722

Reference Type

Journal Article

Year

2014

Language

English

HERO ID 3860722
In Press No
Year 2014
Title Perfluoroalkyl substances in the blood samples from a male population of Sweden
Authors Bao, Jia; Karrman, A; van Bavel, B; Jin, Y
Journal Chinese Science Bulletin
Volume 59
Issue 4
Page Numbers 388-395
Abstract Temporal trends of perfluoroalkyl substances (PFASs) have been determined in the blood samples from several countries globally including a female population in Sweden recently, yet little is known about the time trends in the blood levels of these compounds in Swedish male populations over recent years. In this study, the fourteen target PFASs consisted of four perfluorosulfonates (PFSAs) and ten perfluorocarboxylates (PFCAs) in the whole blood samples, collected from 153 Swedish elderly men during the period between 2008 and 2010, were analyzed via ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). As the dominant PFASs contaminants in the blood samples, perfluorooctane sulfonate (PFOS) showed the highest geometric mean (GM) at 8.5 ng/mL, ranging from 1.7 to 29 ng/mL, while blood perfluorooctanoic acid (PFOA) contained the GM of 1.8 ng/mL, ranging from 0.35 to 6.4 ng/mL. Both the levels of these two compounds were lower than those determined in the blood samples of Swedish elderly populations derived from the late 1990s. According to the temporal trend analysis, over the three years, the blood levels of PFOS in Swedish male populations declined 16 % per annum, while those of perfluoroundecanoic acid (PFUnDA) increased 6.1 % per annum, which were consistent with those reported previously for the populations from other countries.
Doi 10.1007/s11434-013-0008-5
Wosid WOS:000330827900007
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Perfluoroalkyl substances (PFASs); Perfluorooctane sulfonate (PFOS); Blood; Male population; Temporal trend