Acute inhalation toxicity of ammonium perfluorononanoate
Kinney, LA; Chromey, NC; Kennedy, GL
HERO ID
3858726
Reference Type
Journal Article
Year
1989
Language
English
PMID
| HERO ID | 3858726 |
|---|---|
| In Press | No |
| Year | 1989 |
| Title | Acute inhalation toxicity of ammonium perfluorononanoate |
| Authors | Kinney, LA; Chromey, NC; Kennedy, GL |
| Journal | Food and Chemical Toxicology |
| Volume | 27 |
| Issue | 7 |
| Page Numbers | 465-468 |
| Abstract | Ammonium perfluorononanoate (CAS Registry No. 4149-60-4) is a white powder that can become airborne. Its acute inhalation toxicity in male rats was studied. Male rats were exposed for single 4-hr periods to dust concentrations ranging from 67 to 4600 mg/m3. The LC50 was determined to be 820 mg/m3, with the lowest concentration causing death being 590 mg/m3. Ammonium perfluorononanoate was classified as moderately toxic by the acute inhalation route. Exposure to ammonium perfluorononanoate caused a pronounced increase in liver size. The acute toxicity of ammonium perfluorononanoate appears to be similar to that of its 8-carbon homologue, ammonium perfluorooctanoate, but considerably less than that of the 10-carbon homologue, perfluoro-n-decanoic acid. |
| Doi | 10.1016/0278-6915(89)90033-1 |
| Pmid | 2777150 |
| Wosid | WOS:A1989AQ61100006 |
| Url | https://search.proquest.com/docview/79199746?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Air Pollutants; Caprylates; Fluorocarbons; hexadecafluoro-nonanoic acid; 76-21-1; perfluorooctanoic acid; 947VD76D3L; Index Medicus; Animals; Body Weight -- drug effects; Liver -- drug effects; Administration, Inhalation; Organ Size -- drug effects; Liver -- pathology; Caprylates -- toxicity; Fluorocarbons -- toxicity; Air Pollutants -- toxicity |
| Relationship(s) |
|