Experimental studies on human health effects of air pollutants. IV. Short-term physiological and clinical effects of nitrogen dioxide exposure
Hackney, JD; Thiede, FC; Linn, WS; Pedersen, EE; Spier, CE; Law, DC; Fischer, DA
HERO ID
34714
Reference Type
Journal Article
Year
1978
Language
English
PMID
| HERO ID | 34714 |
|---|---|
| In Press | No |
| Year | 1978 |
| Title | Experimental studies on human health effects of air pollutants. IV. Short-term physiological and clinical effects of nitrogen dioxide exposure |
| Authors | Hackney, JD; Thiede, FC; Linn, WS; Pedersen, EE; Spier, CE; Law, DC; Fischer, DA |
| Journal | Archives of Environmental Health |
| Volume | 33 |
| Issue | 4 |
| Page Numbers | 176-181 |
| Abstract | Adult male volunteers were exposed to nitrogen dioxide (NO2) at 1.0 ppm in purified air under conditions simulating ambient photochemical smog exposures (2-hr exposure with intermittent light exercise at 31 degrees C and 35% relative humidity). Sham exposures to purified air alone served as controls. Exposure effects were assessed by pulmonary physiological tests and by a standardized clinical evaluation. No statistically physiological changes attributable to NO2 exposure were found except for a marginal loss in forced vital capacity after exposure on two successive days (1.5% mean decrease, P less than .05). Reported respiratory and other symptoms were slightly increased with exposure as compared to control, but the change was not significant. Short-term toxicity of NO2 at peak ambient concentrations appears to be substantially less than that of ozone in healthy people, but adverse NO2 effects in diseased people or in long-term exposures cannot be ruled out at present. |
| Doi | 10.1080/00039896.1978.10667330 |
| Pmid | 686843 |
| Wosid | WOS:A1978FN51700004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | 1978b in 242,04.Arch. Environ. Health 33: 176-181. |
| Is Public | Yes |
| Language Text | English |
| Is Qa | No |