Long-term NO2 exposure of mice in the presence and absence of vitamin E. II. Effect of glutathione peroxidase
Ayaz, KL; Csallany, AS
HERO ID
33884
Reference Type
Journal Article
Year
1978
Language
English
PMID
| HERO ID | 33884 |
|---|---|
| In Press | No |
| Year | 1978 |
| Title | Long-term NO2 exposure of mice in the presence and absence of vitamin E. II. Effect of glutathione peroxidase |
| Authors | Ayaz, KL; Csallany, AS |
| Journal | Archives of Environmental & Occupational Health |
| Volume | 33 |
| Issue | 6 |
| Page Numbers | 292-296 |
| Abstract | One hundred and twenty female mice fed diets containing various levels of vitamin E were continuously exposed to 0.5 ppM, 1.0 ppM nitrogen dioxide (NO2), and filtered air for 17 months. Blood, lung, and liver tissues were assayed for glutathione peroxidase (GSH-peroxidase) activity. Exposure to 0.5 ppM NO2 did not affect blood and lung GSH-peroxidase activity; 1.0 ppM NO2 exposure however, caused suppression of the enzyme. A combination of vitamin E deficiency and 1.0 ppM NO2 exposure resulted in the lowest GSH-peroxidase activities in the blood and lung. High levels of vitamin E in the diet resulted in elevated GSH-peroxidase in the blood and lung. Liver GSH-peroxidase activity was unaffected by either dietary vitamin E or NO2 exposure. |
| Doi | 10.1080/00039896.1978.10667350 |
| Pmid | 736611 |
| Wosid | WOS:A1978GH44700002 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ECRIB. 2 in NO2 is a subscriptArch. Environ. Health 33: 292-296. |
| Is Public | Yes |
| Language Text | English |