Ruthenium(II) and Osmium(II) Mixed Chelates Based on Pyrenyl-Pyridylimidazole and 2,2 '-Bipyridine Ligands as Efficient DNA Intercalators and Anion Sensors
Mardanya, S; Karmakar, S; Maity, D; Baitalik, S
| HERO ID | 3124068 |
|---|---|
| In Press | No |
| Year | 2015 |
| Title | Ruthenium(II) and Osmium(II) Mixed Chelates Based on Pyrenyl-Pyridylimidazole and 2,2 '-Bipyridine Ligands as Efficient DNA Intercalators and Anion Sensors |
| Authors | Mardanya, S; Karmakar, S; Maity, D; Baitalik, S |
| Journal | Inorganic Chemistry |
| Volume | 54 |
| Issue | 2 |
| Page Numbers | 513-526 |
| Abstract | We report herein the synthesis and characterization of two monometallic ruthenium(II) and osmium(II) complexes of composition [(bpy)2M(HImzPPy)] (ClO4)2 derived from pyrenylimidazole-10-pyridin-2-yl-9H-9,11-diazacyclopenta[e]pyrene (HImzPPy) and 2,2'-bipyridine (bpy) ligands. X-ray crystallographic study shows that both crystals belong to the triclinic system having space group P1̅. The photophysical properties of 1 and 2 in acetonitrile indicate that the metal-to-ligand charge-transfer excited state is mainly centered in the [M(bpy)2](2+) moiety of the complexes and slightly affected by the extended conjugation of the pyrenylimidazole moiety. Both complexes display one-electron reversible metal-centered oxidative processes and a number of quasi-reversible reductive processes. The binding affinities of the complexes toward calf-thymus DNA (CT-DNA) were thoroughly studied through different methods such as absorption, emission, excited-state lifetime, circular dichroism, and thermal denaturation of DNA and a relative DNA binding study using ethidium bromide. All of these experiments account for the intercalative nature of both 1 and 2 toward CT-DNA as well as their light-switch behavior. The anion recognition study through different spectroscopic techniques reveals that both complexes act as "turn-on" luminescence sensors for H2PO4(-) and "turn-off" sensors toward F(-) and AcO(-). The imidazole N-H proton of the receptors gets deprotonated with the excessive addition of F(-) and AcO(-), while it interacts with H2PO4(-) through hydrogen-bonding interaction. Theoretical calculations (DFT and TD-DFT) were also performed to understand the photophysical properties of the metalloreceptors. |
| Doi | 10.1021/ic502271k |
| Pmid | 25539402 |
| Wosid | WOS:000348333400017 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921485350&doi=10.1021%2fic502271k&partnerID=40&md5=ca4d82cc03136f64c32098512ba93d0e |
| Is Public | Yes |
| Language Text | English |