Highly sensitive amperometric Pt-Nafion gas phase nitric oxide sensor: Performance and application in characterizing nitric oxide-releasing biomaterials
Zheng, Z; Ren, H; Vonwald, Ian; Meyerhoff, ME
| HERO ID | 3066605 |
|---|---|
| In Press | No |
| Year | 2015 |
| Title | Highly sensitive amperometric Pt-Nafion gas phase nitric oxide sensor: Performance and application in characterizing nitric oxide-releasing biomaterials |
| Authors | Zheng, Z; Ren, H; Vonwald, Ian; Meyerhoff, ME |
| Journal | Analytica Chimica Acta |
| Volume | 887 |
| Page Numbers | 186-191 |
| Abstract | A highly sensitive amperometric gas-phase nitric oxide (NO) sensor based on a Pt working electrode chemically deposited on a Nafion film is described. The Pt electrode is chemically deposited on a Nafion 117 membrane by impregnating the film with Pt(NH3)(4)(2+) ions, which are then exposed to NaBH4 to precipitate conductive Pt metal. The sensor was characterized with a mass-flow controlled 1 ppm NO standard gas and has an electrochemical surface area of 34 +/- 9 cm(2), low limits of detection (4.3 +/- 1.1 ppb) and a fast response time (<5s) toward changes in gas phase NO levels. Good correlation was found for measurements with the new amperometric Pt-Nafion sensor vs. chemiluminescence results for detecting the rates of NO release from Carbosil2080A polymer films doped with S-nitroso-N-acetylpenicillamine (R = 0.999, m = 0.999, n = 6) and for electrochemical reduction of nitrite to NO (R = 0.999, m = 0.938, n = 3) mediated by a copper(II)-tri(2-pyridylmethyl) amine complex. (C) 2015 Elsevier B.V. All rights reserved. |
| Doi | 10.1016/j.aca.2015.06.016 |
| Pmid | 26320801 |
| Wosid | WOS:000360644100021 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Nitric oxide; S-nitrosothiol; Amperometric gas-phase sensor; Nafion; Electrochemical nitric oxide generation |