Eleventh report on carcinogens: Methylene chloride
HERO ID
3036106
Reference Type
Technical Report
Subtype
NTP
Year
2004
Language
English
| HERO ID | 3036106 |
|---|---|
| Material Type | NTP |
| Year | 2004 |
| Title | Eleventh report on carcinogens: Methylene chloride |
| Book Title | Report on carcinogens: Eleventh edition |
| Authoring Organization | National Toxicology Program |
| Publisher Text | National Toxicology Program |
| City | Research Triangle Park, NC |
| Page Numbers | III136-III137 |
| Abstract | Dichloromethane (methylene chloride) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals (NTP 1986). When administered by inhalation, the compound is carcinogenic in mice and female rats. It caused increased incidences of alveolar/bronchiolar neoplasms and hepatocellular neoplasms in mice of both sexes. Dichloromethane inhalation also increased the incidences of fibroadenoma of the mammary gland in female rats. There is some evidence of the carcinogenicity of dichloromethane in male rats, as shown by an increased incidence of fibroadenoma of the mammary gland (NTP 1986, IARC 1987). No adequate human studies of the relationship between exposure to dichloromethane and human cancer were found (IARC 1979, 1982, 1999). |
| Is Certified Translation | No |
| Dupe Override | No |
| Number Of Pages | 2 |
| Edition | 11th |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
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