Nested Case-Control Study of Leukemia and Ionizing Radiation at the Portsmouth Naval Shipyard
| HERO ID | 2972030 |
|---|---|
| Year | 2004 |
| Title | Nested Case-Control Study of Leukemia and Ionizing Radiation at the Portsmouth Naval Shipyard |
| Volume | GRA and I |
| Abstract | To determine if there is an association between occupational exposure to external ionizing radiation and leukemia mortality among civilian Portsmouth Naval Shipyard workers after potential confounders and effect modifiers such as solvent exposure, and time since exposure are considered. This study employs a nested case-control design and includes 115 leukemia cases and 460 controls. Among the cases and controls, 201 (35%) were monitored for radiation exposure. Badge doses and exposures to work-required medical x-rays were included in the analysis. Benzene and carbon tetrachloride exposure was assessed using workers' job information and industrial hygiene records. Conditional logistic regression was used to analyze the exposure-response relationship between external ionizing radiation exposure and leukemia mortality. A significant positive association was found between leukemia mortality and external ionizing whole-body radiation exposure (OR= 1.08 at 10 mSv; 95% CI=1.01, 1.16) adjusting for gender, radiation worker status and solvent exposure duration. |
| Report Number | NTIS/02936960 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: Govt Reports Announcements and Index ISSN: |
| Is Public | Yes |