Effect of body condition on tissue distribution of perfluoroalkyl substances (PFASs) in Arctic fox (Vulpes lagopus)
Aas, CB; Fuglei, E; Herzke, D; Yoccoz, NG; Routti, H
HERO ID
2851149
Reference Type
Journal Article
Year
2014
Language
English
PMID
| HERO ID | 2851149 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | Effect of body condition on tissue distribution of perfluoroalkyl substances (PFASs) in Arctic fox (Vulpes lagopus) |
| Authors | Aas, CB; Fuglei, E; Herzke, D; Yoccoz, NG; Routti, H |
| Journal | Environmental Science & Technology |
| Volume | 48 |
| Issue | 19 |
| Page Numbers | 11654-11661 |
| Abstract | Arctic animals undergo large seasonal fluctuations in body weight. The effect of body condition on the distribution and composition of 16 perfluoroalkyl substances (PFASs) was investigated in liver, blood, kidney, adipose tissue, and muscle of Arctic foxes (Vulpes lagopus) from Svalbard (n = 18, age 1-3 years). PFAS concentrations were generally highest in liver, followed by blood and kidney, while lowest concentrations were found in adipose tissue and muscle. Concentrations of summed perfluorocarboxylic acids and perfluoroalkyl sulfonates were five and seven times higher, respectively, in adipose tissue of lean compared to fat foxes. In addition, perfluorodecanoate (PFDA) and perfluoroheptanesulfonate (PFHpS) concentrations in liver, kidney, and blood, and, perfluorononanoate (PFNA) in liver and blood, were twice as high in the lean compared to the fat foxes. The ratio between perfluorooctane sulfonamide (FOSA) and its metabolite perfluorooctanesulfonate (PFOS) was lowest in liver, muscle, and kidney, while significantly higher proportions of FOSA were found in adipose tissue and blood. The results of the present study suggest that toxic potential of exposure to PFAS among other pollutants in Arctic mammals may increase during seasonal emaciation. The results also suggest that body condition should be taken into account when assessing temporal trends of PFASs. |
| Doi | 10.1021/es503147n |
| Pmid | 25215880 |
| Wosid | WOS:000343016600079 |
| Url | https://search.proquest.com/docview/1614867782?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Environmental Studies; Metabolites; Pollutants; Comparative analysis; Environmental science |