Alcohol consumption and micronutrient intake as risk factors for liver cirrhosis: A case-control study

Corrao, G; Torchio, P; Zambon, A; D'Amicis, A; Lepore, AR; Di Orio, F; Provincial GROUP FOR THE STUDY OF CHRONIC LIVER, D

HERO ID

2736400

Reference Type

Journal Article

Year

1998

Language

English

PMID

9549000

HERO ID 2736400
In Press No
Year 1998
Title Alcohol consumption and micronutrient intake as risk factors for liver cirrhosis: A case-control study
Authors Corrao, G; Torchio, P; Zambon, A; D'Amicis, A; Lepore, AR; Di Orio, F; Provincial GROUP FOR THE STUDY OF CHRONIC LIVER, D
Journal Annals of Epidemiology
Volume 8
Issue 3
Page Numbers 154-159
Abstract BIOSIS COPYRIGHT: BIOL ABS. PURPOSE: The purpose of this study was to assess the relationship of alcohol consumption and intake of 15 selected micronutrients with risk of liver cirrhosis. METHODS: Data from a case-control study performed in 1989-1990 in central Italy involving 115 incident cases and 167 hospital controls were used. RESULTS: Cases and controls did not differ for mean daily intake of calories, carbohydrates, lipids, and proteins. Significant direct dose-response relationships between the intakes of vitamin A and iron and the risk cirrhosis were observed, while significant protective effects were obtained for the intakes of vitamins B2 (riboflavin) and B12. Different patterns of the joint effect of nutrients and alcohol were also observed. The intakes of vitamin A and iron were significantly associated with the risk of cirrhosis in lifetime teetotalers (odds ratios (OR) and 95% confidence intervals (CI) of 33.6 (1.2-979.9) and 37.9 (1.8-819.4) for higher intake of vitamin A and iron,
Pmid 9549000
Wosid WOS:000072649800003
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword alcohol consumption; diet; interaction; liver cirrhosis; micronutrients; iron; vitamin A; vitamin B-12; riboflavin; case-control study
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